Combining Psilocybin Microdosing and CBD

There are so many reported and studied benefits of both Psilocybin mushrooms and cannabidiol, more commonly known as CBD. Combining 2 powerful healing substances, a microdose of Psilocybin mushrooms and a dose of CBD tincture, has the potential to offer even greater benefit than either of these 2 medicines offer on their own. 

While there is currently much speculation about the purported benefits of microdosing mushrooms, the positive reports from those who microdose are too numerous to ignore. Scientific communities around the world are currently seeking government permission and funding as they are interested in conducting research around the safety and effectiveness of using substances with psychoactive components to support healing. 

As these substances gain recognition and scientific validation, there is hope that they will be recognized as better psychiatric medicines that improve the quality of life, health and happiness of patients suffering from symptoms that range from mild to very severe. 

Grassroots Medicinal offers a Rest and Reset Package with a full month’s supply of microdose mushrooms and CBD tincture. Try it and decide for yourself what to think of the benefits. Our goal is to support healing on multiple levels offering pure plant medicine. 

Why Combine CBD and a Microdose of Mushrooms? 

On their own, both of these natural substances offer a multitude of benefits for health and wellness in many areas: physical, mental, emotional and for some, spiritual. The body responds well to many natural medicines because they are recognized by human systems. Many plant and mushroom medicines have profound healing effects on the body and brain. 

Often when we combine natural medicines together in an amount that is safe for the human body, we experience exponential benefits due to the synergy or combined effects of the medicines. Some natural medicines have the potential to amplify or increase the healing benefits when used in combination with other natural medicines. In other words, the sum is greater than 1 mushroom microdose and 1mL or 1 ounce of CBD tincture. 

While deeper research is needed to create clarity on whether or not there are negative long term side effects from microdosing, many people are enjoying the benefits microdosing offers. Further to this, people who use these substances for healing come from many demographics and communities.

CBD, which is non-psychoactive and legally available in the US and Canada, has been well-researched for its benefits and effects on the brain and the body. Many published reports and articles provide evidence that supports using CBD for healing a multitude of symptoms and conditions. . 

The powerful Rest and Reset duo combines the power of psilocybe mushrooms and CBD to offer: 

  • a full night’s sleep and relief from insomnia
  • elevated immune system
  • improved memory
  • increased focus throughout the day 

It has also been reported that combining mushroom microdosing and CBD can:

  • Boost mood
  • Improve task efficiency and performance  
  • Lower stress and anxiety
  • Support and elevate mental health 
  • Reduce inflammation
  • Decrease oxidative stress/damage

Microdosing mushrooms seems to further support lowering stress by minimizing and even eliminating possible negative side effects from CBD. The 2 substances together work quickly and effects are experienced 30 or so minutes after ingestion. The dosage seems to last about 6 hours, allowing time for deep rest and relaxation so healing can occur. Because the body does much of its healing while asleep, a good sleep is believed to be at the foundation of human wellness. Many people experience long term benefits after short term use without negative side effects. 

Learn more about the benefits of CBD and microdosing mushrooms and how they might support your wellness. 

Using the Rest and Reset Kit

Safety is always of the utmost importance, so we always recommend speaking to a medical professional to determine what is best for you. The Rest and Rest Package provides the recommended dosage for a month’s worth of medicine. This is what we believe provides the maximum benefit. 

The Grassroots Medicinal offers a microdose capsule carefully formulated and measured to support your wellness without providing a psychoactive experience. Our goal is to support and empower healing with natural medicine and it’s important that you educate yourself and get expert advice before taking any medicine, natural or otherwise. 

Taking the mushroom microdose

Learn  how to microdose in a way that works best for you by reading our blog and by downloading our guide to microdosing. For the Rest and Reset Package, many people take a microdose daily; be sure to find the right protocol/method for you and always seek the advice of your doctor or medical health professional. 

How to use the CBD tincture

Our CBD is provided in isolate form. One bottle of CBD tincture contains 1000mg 30ml (1oz) CBD isolate tincture and the dropper allows for careful measuring of one full month’s dosage. For maximum benefit, it is recommended that tinctures are taken under the tongue (sublingually) to help the CBD enter the bloodstream quickly and efficiently. 


The Grassroots Medicinal uses products and raw materials that are ethically and locally sourced and grown, to ensure freshness, purity and quality. We are committed to providing the best quality products to you and all our products are organically grown. Learn more about us here

We are thrilled to have the opportunity to support your health and wellness, naturally! 

Deepen your learning

What is microdosing:

Download the guide:

Microdose with Intention:

Psilocybin Therapy: